ஆண்களுக்கு பெரிய பிரச்சினை ஆரம்பிப்பது அவர்கள் இளம் வயதிலேயே தலை முடி உதிர ஆரம்பிக்கும்போது. அதேபோல் பெண்களுக்கு முகத்தில் லேசாக மீசை வளர்வதும் ஒரு சின்ன குறைபாடு. இது இரண்டுமே நடப்பது அவர்கள் உடலில் செக்ஸ் ஹார்மோன் சுரக்க ஆரம்பித்த பிறகு. அதாவது பொதுவாக பதின்ம வயதுக்கு மேல். இந்த குறைபாடு ஒரு மாதிரியான ஹார்மோனல் இம்பேலண்ஸால்தான்.
இது இரண்டுக்குமே காரணமான ஒரு ஹார்மோன் டைஹைட்ரோடெஸ்டாஸ்டீரோன் என்கிற ஒரு ஸ்டெராயிட்.
இது ஆண் செக்ஸ் ஹார்மோன் டெஸ்ட்டாஸ்டீரோனுடைய மெட்டபொலைட். டெஸ்டாஸ்டீரோனுடைய ரிடக்சன் ப்ராடக்ட்னு சொல்லலாம். ஆனால் இதை டெஸ்டாஸ்டீரோனாக திரும்ப மாற்ற முடியாது. It is an irreversible process.
கொலெஸ்டிரால் (we all know excess of cholesterol presence can cause heart disease) என்கிற ஸ்டெராயிட் மனிதனுக்கு மிகவும் முக்கியமான ஒரு லிப்பிட். அது இல்லாமல் மனிதன் வாழமுடியாது. கொலெஸ்டிராலில் இருந்துதான் இந்த ஆண் மற்றும் பெண் செக்ஸ் ஹார்மோன்கள் டெஸ்டாஸ்டீரோன் மற்றும் எஸ்ட்ரோஜன்ஸ் உருவாகிறது.
ஆண்களுக்கு டெஸ்டாஸ்டீரரோன் என்கிற ஹார்மோன் கொலெஸ்டிராலி லிருந்து உருவாக்கப்படுகிறது. அதாவது கொலெஸ்டிராலை டெஸ்டோஸ்டீரோனாக மாற்றத் தேவையான என்சைம்கள் ஆண்களிடம் இருக்கின்றன.
அதே சமயம் பெண்களுக்கு எஸ்ட்ரோஜென் என்கிற ஹார்மோன்கள் கொலெஸ்டிராலில் இருந்து உருவாகிறது. பெண்களுக்கும் முதலில் டெஸ்டாஸ்டேரோன் தான் உருவாகிறது, பிறகு இது எஸ்ட்ரொஜெனாக மாற்றப்படுகிறது. அதற்கு தேவையான என்சைம், அரொமட்டேஸ் என்கிற ஒன்று. இந்த என்சைம் பெண்களுக்கு மட்டும்தான் இருக்கிறது. ஆண்களுக்கு கிடையாது. அதனால் பெண்களுக்கு உருவாகும் டெஸ்டாஸ்டீரோன், அத்தோடு நிற்காமல் எஸ்ட்ரோஜெனாக மாறிவிடுகிறது. இதுதான் பெண்களின் மார்பக வளர்ச்சிக்கு மற்றும் பல விசயங்களுக்கு காரணமானது. ஆண்களுக்கு அரொமடேஸ் என்கிற இந்த என்சைம் இருப்பது கிடையாது. அதனால் அது டெஸ்டாஸ்டீரோனுடன் நின்றுவிடுகிறது.
Dihydrotestosterone is believed to be responsible for developing baldness in men and for the growth of facial and body hair in women. This steroid is also important for men for being a "man". When the amount of this steroid becomes little bit more excess it causes baldness in men. Also, females have a very little testosterone compared to men, which is also believed to be responsible for their sexual drive. But if they have little more excess and get converted to dihydrotestosterone, it causes some trouble like facial hair and body hair of that sort of abnormalities. The same DHT is one which is causing the formation facial and body hair in men as well
DHT? Die Hard Testosterone?
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If you are noticing that your hair has been thinning progressively, then it's highly likely that DHT is the primary cause of your condition. Male Pattern Baldness or Androgenetic Alopecia is a progressive hair loss condition where your hair line reclines from the top and also possible from the front of your head.
For many centuries, there had been a lot of theories about the balding condition among men and it's not till the late 20th century where scientists had finally declared that, this male hormone is responsible for stripping of the crown of a few too many good men.
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The Male Hormone Testosterone
It all begins with the single male hormone known as Testosterone, a principal male sex hormone and an anabolic steroid that is responsible for regulating health and well-being. The main responsibilities of this hormone is to
increase libido (sex drive)
increase energy
increase production of red blood cells
Testosterone is also present in females but in a much lesser quantities. Research shows that an average adult man has about forty to sixty times the amount of testosterone compared to an adult woman, a very big contrast indeed. Although women have far lesser amounts of this hormone, they are more much sensitive to it than men.
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What is it?
DHT stands for Dihydrotestosterone (Die-hi-dro-tes-tos-ter-ron) an active metabolite and also a by product of the male sex hormone Testosterone. Metabolites are compounds that are crucial for normal growth, physical development and reproduction.
This compound is also known as an androgenic hormone, which main functions are to control and boost the development of your male characteristics. Besides that, DHT is also important to suppress the effects of the female's hormone estrogen that is also found in men.
Your prostate glands, testes, hair follicles and andrenal glands are responsible for converting the male hormone Testosterone into DHT when they release an enzyme known as 5 alpha reductase which binds with this male hormone.
Some of the common roles of this androgen are
acne
male voice
male masculinity
nose hairs
male puberty
beards and body hair
In simpler words, this particular hormone gives you the male characteristics and the manliness a man should be.
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How can it cause Male Pattern Baldness?
The most important question of all. The problem with this supposedly powerful hormone and great ally for men so happens to also have a 'dark side' as it is also found to be the primary cause of Male Pattern Baldness. When the converted hormone in the blood streams reaches your scalp, it
binds with the androgen receptors on your hair follicle
Blocks and interrupt with the normal growth of the hair follicle
prevents essential nutrients and oxygen that fuels your follicle
Over time, your hair follicles will produce finer and finer hair through each hair growth cycle. The growing phase (ANAGEN) of your hair will also be shortened until it loses the ability to grow terminal hairs. By looking at the illustration above, you can briefly see how the miniaturization process begins.
Over time, your hair follicles will produce finer and finer hair through each hair growth cycle. The growing phase (ANAGEN) of your hair will also be shortened until it loses the ability to grow terminal hairs.
If this process continues, you will see the affected hairs getting thinner and frail and soon these 'vellus hairs' will be fine enough to even notice them. As this goes on, the hairs will fall out and the hair follicles will gradually shut down and when it does, it's gone forever.
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How to reduce it?
If you can remove these hormones from accumulating in your hair follicles, you can effectively prevent further hair loss caused by Male Pattern Baldness. There are a lot of effective and proven treatments like Propecia and Minoxidil that can stop and even reverse this condition but there are a lot of critical steps that you must take and understand first before beginning treatment.
Also, please read the other essential factors that can cause hair loss in my Preventing Hair Loss Section when you are ready. Before checking out the products, you might want to take a look at the Hamilton Norwood Scale to determine the seriousness of your MPB condition.
If your hair loss just happens suddenly, then you are likely not related to Dihydrotestosterone. You might want to check out my Other Hair Loss Causes page and also Telogen Effluvium for more information.
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